As of the 16th of May 2021 the cumulative number of COVID-19 cases identified in South Africa is 1 611 143.
| Province | Total cases for 15 May 2021 | Percentage total |
| Eastern Cape | 196 554 | 12,2 |
| Free State | 94 274 | 5,9 |
| Gauteng | 433 819 | 26,9 |
| KwaZulu-Natal | 337 923 | 21,0 |
| Limpopo | 64 414 | 4,0 |
| Mpumalanga | 79 808 | 5,0 |
| North West | 70 749 | 4,4 |
| Northern Cape | 44 031 | 2,7 |
| Western Cape | 289 571 | 18,0 |
| Unknown | 0 | 0,0 |
| Total | 1 611 143 | 100,0 |
Testing Data
The number of tests conducted to date is 11 087 505. Of these 34 512 tests were conducted since the last report.
| Sector | Total tested | New tested | ||
| PRIVATE | 6 231 265 | 56% | 20 409 | 59% |
| PUBLIC | 4 856 240 | 44% | 14 103 | 41% |
| Total | 11 087 505 | 34 512 |
Deaths and Recoveries
59 COVID-19 related deaths have been reported: Eastern Cape 0, Free State 5, Gauteng 20, KwaZulu-Natal 8, Limpopo 0, Mpumalanga 2, North West 0, Northern Cape 18 and Western Cape 6 which brings the total to 55 183 deaths. We convey our condolences to the loved ones of the departed and thank the health care workers who treated the deceased patients, said Dr. Zwelini Mkhize .
The cumulative recoveries now stand at 1 523 243 representing a recovery rate of 94,5%.
| Province | Total Deaths | Total Recoveries | Active Cases |
| Eastern Cape | 11 615 | 184 612 | 327 |
| Free State | 4 016 | 84 953 | 5 305 |
| Gauteng | 10 865 | 415 375 | 7 579 |
| KwaZulu-Natal | 10 454 | 321 777 | 5 692 |
| Limpopo | 2 336 | 61 662 | 416 |
| Mpumalanga | 1 415 | 77 284 | 1 109 |
| North West | 1 798 | 64 489 | 4 462 |
| Northern Cape | 978 | 37 491 | 5 562 |
| Western Cape | 11 706 | 275 600 | 2 265 |
| Total | 55 183 | 1 523 243 | 32 717 |
Vaccination Rollout
The number of vaccinations completed under the Sisonke Protocol as at 18.30 today is 478 452.